
A new study using high-resolution EEG reveals that psilocybin dramatically alters brain connectivity in rats. The psychedelic induced dose-dependent changes in network organization, disrupting normal patterns of neural communication and suggesting rodents may be viable models for studying altered consciousness.

Sacred Plant Alliance (SPA), a coalition of established entheogenic churches, plans to sue the DEA for violating religious freedom laws. SPA argues the DEA’s current exemption process is unlawful, lacks transparency, and hinders sincere religious practice. The lawsuit seeks a fair, legally compliant process for sacramental substance use.

The 3rd Indigenous Peoples Union Festival blended celebration and resistance, bringing together 20 ethnic groups to share songs, rituals, and stories. It reaffirmed identity, denounced cultural appropriation, honored ancestral knowledge, and advocated for rights, land, and climate justice. Art, spirituality, and dialogue shaped a collective vision rooted in tradition and aimed at the future.

A new study finds that individuals with treatment-resistant depression experienced similar improvements from psilocybin-assisted psychotherapy whether or not they had recently discontinued antidepressant medications.

Chacruna Institute has received a $150,000 grant from Kindred Trust to support its work on psychedelic plant medicine research, education, and justice. $100,000 will go to funding the Indigenous Reciprocity Initiative; $50,000 will go to supporting programming. The grant strengthens Chacruna’s mission to center equity, cultural awareness, and inclusion in the evolving psychedelic movement.

Psilocybin significantly enhances psychological well-being and spiritual insight among clergy members across major world religions. Participants reported lasting positive changes in religious practice, personal beliefs, and vocational effectiveness after two guided psilocybin sessions.

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The Church of the Celestial Heart secured U.S. legal protection to use ayahuasca as a religious sacrament after a decade-long battle. Following arrests and government seizures, the church proved its sincerity through extensive documentation and legal persistence. This decision affirms the legal rights of syncretic psychedelic faiths in the United States.
We got our hands on a classic. Trinity Penis Envy, a cross between Penis Envy and the elusive Trinity, which itself is a B+/Penis Envy cross puts the vibe into vibrant let's dive in.

A detailed case report describes how a 21-year-old man died from self-inflicted ocular trauma during a bad psilocybin trip. The tragic event illustrates how rare but extreme reactions to psychedelics can lead to fatal outcomes.

In a unique real-world study, researchers examined the psychological effects of trauma on survivors of the October 7 Nova Festival attack in Israel, focusing on their use of mind-altering substances. Among 343 participants, those who had taken classic psychedelics like LSD or psilocybin reported significantly lower anxiety and PTSD symptoms than those who used other substances or none at all.
For the first time in the states history, Oklahoma hosted a magic mushroom cup that will surely be hitting your platter in no time.
As Big Pharma cashes in on psychedelics, can we avoid selling out the soul of the counterculture?

Fernanda Palhano's research group in Brazil explores the therapeutic potential of psychedelics like ayahuasca and DMT through interdisciplinary collaboration. Despite regulatory, funding, and institutional challenges, they’ve built innovative clinical trials, training programs, and a research center—committed to ethical, inclusive, and accessible mental health care grounded in science and traditional knowledge. The post Science, Spirit, and Structure: Building a Psychedelic Research Hub in Brazil’s Public University System appeared first on Chacruna.

A recent study found that a single moderate dose of psilocybin produced lasting antidepressant-like effects in rats, while higher doses led to unwanted side effects. The findings highlight the importance of optimal dosing.

At this year’s Psychedelic Science 2025 conference, Chacruna Institute is proud to offer various activities and spaces for the public to participate in. The post Meet Chacruna at Psychedelic Science 2025 appeared first on Chacruna.
Oregon leads the US in legal psilocybin therapy, but soaring costs and equity gaps spark debate. Explore the highs and lows of the shroom boom.

A new study using brain scans found that psilocybin and escitalopram reduce depression symptoms through different neural mechanisms. While escitalopram dampened emotional brain activity, psilocybin preserved or slightly increased it, suggesting distinct pathways to recovery.

The UAE is leading a cultural and scientific shift in the Middle East by exploring the therapeutic potential of psychedelics, merging innovation with tradition to reshape mental health care and global perceptions. The post An Arab Nation’s Psychedelic Awakening appeared first on Psychedelic Scene Magazine.

The intersection of queerness and psychedelics remains underexplored in academic research, despite psychedelics' potential for queer identity development and healing. A recent scoping review highlights gaps in representation, calls for intersectional, non-pathologizing approaches, and emphasizes the importance of centering queer experiences to enrich psychedelic research, therapy, and human flourishing overall. The post The Queer Potential of Psychedelics: Assessing Queer Representation in the Academic Literature of Psychedelic Studies appeared first on Chacruna.

Discover Just Like Gold: Live At The Matrix, the first official release from 1960s San Francisco band The Final Solution, featuring rare live recordings and archival material from High Moon Records. The post High Moon Records Releases Just Like Gold: Live At The Matrix by The Final Solution appeared first on Psychedelic Scene Magazine.

Join us for this dialogue that delves into the exciting intersections between psychedelics and attachment theory. The post Psychedelics and Attachment: Fundamentals, Implications, and New Frontiers appeared first on Chacruna.

A new theory suggests that psychedelics promote empathy, insight, and psychological flexibility by making the brain’s right hemisphere temporarily dominant over the left. Known as HEALS—Hemispheric Annealing and Lateralization Under Psychedelics—this model proposes that psychedelics disrupt the typical hierarchy between hemispheres, releasing the more holistic, emotionally intelligent right side from left-brain control.

Finally evidence shows that psychedelics do improve brain function. And, frequency of consumption is part of the ‘how’. A recent study highlighted by PsyPost further illuminates these benefits, particularly linking psychedelic experiences to long-term improvements in psychological flexibility, a concept we’ll explore here. This is where microdosing psychedelics has the most positive impact, even though... Continue Reading → The post Psychedelic experiences linked to long-term improvements in psychological flexibility, study finds appeared first on Psychedelic Integration.

Choosing the right 5-MeO-DMT facilitator is critical for a safe and transformative journey. This article explores why trauma-informed care, proper training, and ethical guidance are essential when navigating this powerful psychedelic experience. The post Choosing Your Guide appeared first on Psychedelic Scene Magazine.

Jeffrey Alexander + The Heavy Lidders return with Synchronous Orbit, a genre-blurring psych journey blending studio precision and live improvisation. Featuring contributions from Kate Wright and Isaiah Collier, the album offers a rich, cosmic trip across time and space. The post Jeffrey Alexander + The Heavy Lidders Release New Album Synchronous Orbit appeared first on Psychedelic Scene Magazine.

A new open-label study suggests that a single dose of psilocybin, combined with psychological support, may reduce symptoms in people with severe treatment-resistant depression. Improvements were sustained for up to 12 weeks, although effects were weaker in those with PTSD.