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Psilocybin induces large-scale brain network reorganization, offering insights into the psychedelic state

Posted: 6/14/2025

A new study using high-resolution EEG reveals that psilocybin dramatically alters brain connectivity in rats. The psychedelic induced dose-dependent changes in network organization, disrupting normal patterns of neural communication and suggesting rodents may be viable models for studying altered consciousness.

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Sacred Plant Alliance to Sue DEA Over Religious Exemption Process

Posted: 6/13/2025

Sacred Plant Alliance (SPA), a coalition of established entheogenic churches, plans to sue the DEA for violating religious freedom laws. SPA argues the DEA’s current exemption process is unlawful, lacks transparency, and hinders sincere religious practice. The lawsuit seeks a fair, legally compliant process for sacramental substance use.

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United in Fight and Celebration: The 3rd Indigenous Peoples Union Festival

Posted: 6/12/2025

The 3rd Indigenous Peoples Union Festival blended celebration and resistance, bringing together 20 ethnic groups to share songs, rituals, and stories. It reaffirmed identity, denounced cultural appropriation, honored ancestral knowledge, and advocated for rights, land, and climate justice. Art, spirituality, and dialogue shaped a collective vision rooted in tradition and aimed at the future.

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Psilocybin therapy shows similar benefits for patients with and without recent antidepressant use

Posted: 6/11/2025

A new study finds that individuals with treatment-resistant depression experienced similar improvements from psilocybin-assisted psychotherapy whether or not they had recently discontinued antidepressant medications.

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Press Release – Chacruna Receives $150,000 Grant from Kindred Trust

Posted: 6/10/2025

Chacruna Institute has received a $150,000 grant from Kindred Trust to support its work on psychedelic plant medicine research, education, and justice. $100,000 will go to funding the Indigenous Reciprocity Initiative; $50,000 will go to supporting programming. The grant strengthens Chacruna’s mission to center equity, cultural awareness, and inclusion in the evolving psychedelic movement.

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Psilocybin Elevates Spiritual Awareness

Posted: 6/10/2025

Psilocybin significantly enhances psychological well-being and spiritual insight among clergy members across major world religions. Participants reported lasting positive changes in religious practice, personal beliefs, and vocational effectiveness after two guided psilocybin sessions.

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Events Production Internship (OPEN)

Posted: 6/10/2025

Role: Events Production Internship Location: Remote, with opportunities for travel to conferences/eventsReports to:  Development and Operations OfficerJob Type: Unpaid InternshipDuration: 6 months (minimum) — 1 year (preferred)Hours: 2 hrs per […]

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Church of the Celestial Heart Wins Legal Protection for Ayahuasca Use

Posted: 6/9/2025

The Church of the Celestial Heart secured U.S. legal protection to use ayahuasca as a religious sacrament after a decade-long battle. Following arrests and government seizures, the church proved its sincerity through extensive documentation and legal persistence. This decision affirms the legal rights of syncretic psychedelic faiths in the United States.

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Going Deep With Trinity Penis Envy: Psychedelic Review

Posted: 6/8/2025

We got our hands on a classic. Trinity Penis Envy, a cross between Penis Envy and the elusive Trinity, which itself is a B+/Penis Envy cross puts the vibe into vibrant let's dive in.

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21-year-old man dies after jabbing pencil into his brain during psilocybin trip

Posted: 6/5/2025

A detailed case report describes how a 21-year-old man died from self-inflicted ocular trauma during a bad psilocybin trip. The tragic event illustrates how rare but extreme reactions to psychedelics can lead to fatal outcomes.

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Hallucinogens Linked to Milder PTSD

Posted: 6/4/2025

In a unique real-world study, researchers examined the psychological effects of trauma on survivors of the October 7 Nova Festival attack in Israel, focusing on their use of mind-altering substances. Among 343 participants, those who had taken classic psychedelics like LSD or psilocybin reported significantly lower anxiety and PTSD symptoms than those who used other substances or none at all.

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The 2025 Oklahoma Magic Mushroom Cup Lab Tested Heavy Hitters That'll Rewire Your Reality

Posted: 5/31/2025

For the first time in the states history, Oklahoma hosted a magic mushroom cup that will surely be hitting your platter in no time.

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The Psychedelic Gold Rush: How Corporations Are Co-Opting Counterculture for Profit

Posted: 5/28/2025

As Big Pharma cashes in on psychedelics, can we avoid selling out the soul of the counterculture?

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Science, Spirit, and Structure: Building a Psychedelic Research Hub in Brazil’s Public University System

Posted: 5/28/2025

Fernanda Palhano's research group in Brazil explores the therapeutic potential of psychedelics like ayahuasca and DMT through interdisciplinary collaboration. Despite regulatory, funding, and institutional challenges, they’ve built innovative clinical trials, training programs, and a research center—committed to ethical, inclusive, and accessible mental health care grounded in science and traditional knowledge. The post Science, Spirit, and Structure: Building a Psychedelic Research Hub in Brazil’s Public University System appeared first on Chacruna.

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Only a specific dose of psilocybin induces lasting antidepressant-like effects, study suggests

Posted: 5/27/2025

A recent study found that a single moderate dose of psilocybin produced lasting antidepressant-like effects in rats, while higher doses led to unwanted side effects. The findings highlight the importance of optimal dosing.

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Meet Chacruna at Psychedelic Science 2025

Posted: 5/27/2025

At this year’s Psychedelic Science 2025 conference, Chacruna Institute is proud to offer various activities and spaces for the public to participate in. The post Meet Chacruna at Psychedelic Science 2025 appeared first on Chacruna.

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Oregon’s Shroom Boom: Healing or Hype?

Posted: 5/25/2025

Oregon leads the US in legal psilocybin therapy, but soaring costs and equity gaps spark debate. Explore the highs and lows of the shroom boom.

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Psilocybin and escitalopram produce antidepressant effects via distinct brain mechanisms, study suggests

Posted: 5/25/2025

A new study using brain scans found that psilocybin and escitalopram reduce depression symptoms through different neural mechanisms. While escitalopram dampened emotional brain activity, psilocybin preserved or slightly increased it, suggesting distinct pathways to recovery.

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An Arab Nation’s Psychedelic Awakening

Posted: 5/21/2025

The UAE is leading a cultural and scientific shift in the Middle East by exploring the therapeutic potential of psychedelics, merging innovation with tradition to reshape mental health care and global perceptions. The post An Arab Nation’s Psychedelic Awakening appeared first on Psychedelic Scene Magazine.

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The Queer Potential of Psychedelics: Assessing Queer Representation in the Academic Literature of Psychedelic Studies

Posted: 5/21/2025

The intersection of queerness and psychedelics remains underexplored in academic research, despite psychedelics' potential for queer identity development and healing. A recent scoping review highlights gaps in representation, calls for intersectional, non-pathologizing approaches, and emphasizes the importance of centering queer experiences to enrich psychedelic research, therapy, and human flourishing overall. The post The Queer Potential of Psychedelics: Assessing Queer Representation in the Academic Literature of Psychedelic Studies appeared first on Chacruna.

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High Moon Records Releases Just Like Gold: Live At The Matrix by The Final Solution

Posted: 5/18/2025

Discover Just Like Gold: Live At The Matrix, the first official release from 1960s San Francisco band The Final Solution, featuring rare live recordings and archival material from High Moon Records. The post High Moon Records Releases Just Like Gold: Live At The Matrix by The Final Solution appeared first on Psychedelic Scene Magazine.

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Psychedelics and Attachment: Fundamentals, Implications, and New Frontiers

Posted: 5/16/2025

Join us for this dialogue that delves into the exciting intersections between psychedelics and attachment theory. The post Psychedelics and Attachment: Fundamentals, Implications, and New Frontiers appeared first on Chacruna.

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Psychedelics May Shift Brain Power to the Right Hemisphere

Posted: 5/16/2025

A new theory suggests that psychedelics promote empathy, insight, and psychological flexibility by making the brain’s right hemisphere temporarily dominant over the left. Known as HEALS—Hemispheric Annealing and Lateralization Under Psychedelics—this model proposes that psychedelics disrupt the typical hierarchy between hemispheres, releasing the more holistic, emotionally intelligent right side from left-brain control.

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Psychedelic experiences linked to long-term improvements in psychological flexibility, study finds

Posted: 5/15/2025

Finally evidence shows that psychedelics do improve brain function. And, frequency of consumption is part of the ‘how’. A recent study highlighted by PsyPost further illuminates these benefits, particularly linking psychedelic experiences to long-term improvements in psychological flexibility, a concept we’ll explore here. This is where microdosing psychedelics has the most positive impact, even though... Continue Reading → The post Psychedelic experiences linked to long-term improvements in psychological flexibility, study finds appeared first on Psychedelic Integration.

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Choosing Your Guide

Posted: 5/15/2025

Choosing the right 5-MeO-DMT facilitator is critical for a safe and transformative journey. This article explores why trauma-informed care, proper training, and ethical guidance are essential when navigating this powerful psychedelic experience. The post Choosing Your Guide appeared first on Psychedelic Scene Magazine.

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Jeffrey Alexander + The Heavy Lidders Release New Album Synchronous Orbit

Posted: 5/12/2025

Jeffrey Alexander + The Heavy Lidders return with Synchronous Orbit, a genre-blurring psych journey blending studio precision and live improvisation. Featuring contributions from Kate Wright and Isaiah Collier, the album offers a rich, cosmic trip across time and space. The post Jeffrey Alexander + The Heavy Lidders Release New Album Synchronous Orbit appeared first on Psychedelic Scene Magazine.

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A single dose of psilocybin might help reduce symptoms in treatment-resistant depression

Posted: 5/12/2025

A new open-label study suggests that a single dose of psilocybin, combined with psychological support, may reduce symptoms in people with severe treatment-resistant depression. Improvements were sustained for up to 12 weeks, although effects were weaker in those with PTSD.